Find your gene regulatory pathways, biomarkers, and drug targets in a few clicks

No-coding

Bioinformatics

Academy

For molecular biologists and clinical researchers

Synthetic promoters design — Q&A Session of Coffee Break with TRANSFAC

“Intelligent design” of promoters: Practical Guide

In this webinar Dr. Alexander Kel, the CEO and CSO of geneXplain GmbH, will show how artificial promoters can be constructed with software tools using machine learning (ML) and artificial intelligence (AI) approaches, based on data collected in TRANSFAC. After a short summary on the architecture of promoters and enhancers and on the use of artificial promoters in gene therapy and in other applications, Alexander will give a step-by-step guide for construction and evaluation of artificial promoters and their tissue- and context-specificity. The following main questions will be in the focus of this seminar:

Summary on artificial promoters and enhancers and their application
Machine learning and artificial intelligence approaches for predicting tissue-specific promoter activity
Introduction into tools for construction of artificial promoters
Demonstration of automatic promoter analysis pipeline
Step by step demo of promoter construction and evaluation

Schedule

November 12, 10 AM CET
1 hour
FREE online event

Book Your Seat Get more details…

Key benefits

No-coding bioinformatics

Perform cutting edge bioinformatics analysis in a user-friendly interface with no programming skills needed

Multi-omics

Learn how to process and integrate various omics data types in your analysis

Promoter analysis

Become the gene regulation expert with deep understanding of transcription factors interplay in various conditions

Pathway analysis

Discover the master regulators governing the studied biological processes through intracellular signaling pathways

Disease molecular mechanisms

Identify prospective biomarkers and drug targets for the pathologies of your interest by performing integrated promoter and pathway analysis

Gold standard tools and databases

Learn how to use the best-in-class knowledge bases on genes, proteins, transcription factors, pathways, drugs, and their targets, together with integrated tools

Testimonials

GeneXplain’s databases and software tools are very helpful for our research. The training program is absolutely amazing. It clearly shows to my students how to maximize results of analysis of our omics data! They can learn all the steps of the analysis – from raw data preprocessing to unraveling the hidden molecular mechanisms behind the pathology we’re studying

DR. SUDIPTO DAS

Royal College Of Surgeons In Ireland (RCSI), Lecturer, Pharmacy And Biomolecular Sciences

The geneXplain “Click and Run” bioinformatics approach is absolutely perfect for my needs! I’ve discovered how to uncover the biological significance hidden within my data.

Maria Smetanina

Baylor College of Medicine, Houston, Texas, USA

Coming soon

My way from promoters to pathways

Paid course, €299 per seat before VAT. Date and time will be announced soon.

In this course we will:

review the basic principles of gene regulation
discuss the evolutional advantages of high plasticity of gene regulatory networks
look at real case examples where computational methods are applied for identification of disease biomarkers, drug discovery and personalised medicine
learn several techniques of finding promoters and enhancers and the principles on which these methods are based on
construct workflows „From genome to drug targets“ using the geneXplain platform